Sickle Cell Anaemia

Also known as

  • Sicke cell disorder

Sickle cell anaemia is a genetic disorder that affects the haemoglobin. The Haemoglobin in the marrow produces the red blood cells. In patients with Sickle cell disorder, the red blood cells are sickle in shape and not round, this is because they lack oxygen and grow abnormally.

Condition details

Due to the lack of oxygen these cells tend to be sticky and clump frequently within the blood vessels, thereby forming clots which cause sickling episodes called CRISES. Sickle cell disease is caused by a change to chromosome 11 in the body and is more commonly found in Black and Minority ethnic groups from Africa and the Caribbean

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Photos of affected individuals

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  • No baby imageBaby
  • No toddler imageToddler
  • No child 4-10 imageChild 4-10
  • No child 10-18 imageChild 10-18
  • No adult imageAdult

Typical age range of first manifestation

  • Can manifest in Baby
  • Can manifest in Toddler
  • Can manifest in Child 4-10
  • Can manifest in Child 10-18
  • Can manifest in Adult


Affected genes identified to date

Inheritance patterns

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