Medium-chain Acyl CoA Dehydrogenase Disorder

Also known as

  • MCADD
  • MCAD Disorder

Medium-chain acyl-CoA dehydrogenase deficiency (MCADD) is a rare genetic condition where a person has problems breaking down fatty acids for energy

Condition details

This means that if they go for long periods without eating, they can experience a range of unpleasant symptoms, such as: feeling very tired and sluggish being sick seizures (fits) Left untreated, MCADD can lead to more serious complications – such as coma, brain damage and liver failure – and can sometimes be fatal. Symptoms can be triggered once a baby has stopped receiving regular nightly feeds. There have also been cases where symptoms begin shortly after birth, due to an interruption in a newborn baby’s feeding. Symptoms may also occur when your baby is ill.

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Photos of affected individuals

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  • No baby imageBaby
  • No toddler imageToddler
  • No child 4-10 imageChild 4-10
  • No child 10-18 imageChild 10-18
  • No adult imageAdult

Typical age range of first manifestation

  • Can manifest in Baby
  • Does not manifest in Toddler
  • Does not manifest in Child 4-10
  • Does not manifest in Child 10-18
  • Does not manifest in Adult

Symptoms

Affected genes identified to date

Inheritance patterns

Are carriers affected?

How many are affected?

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Known experts

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